Radiological Society of North America, 74th Scientific Assembly and Annual Meeting of the Radiologic Society of North America, Chicago, Illinois, 27 November-2 December. Radiology, 169(P Supplement):239, November 1988.
Isolation of a feature of interest and correction of partial volume effects is desirable in tissue volume calculations. A linear filter that has excellent segmentation characteristics and produces an image in which partial volume averaging effects are corrected has been applied to MR spin-echo image sequences. Phantom studies on simple cavities show the volume calculations to have a accuracy of better than 3%, with a standard deviation of better than 1.5% in repeated measures. A comparison with simple threshold pixel counting shows this weighted pixel counting technique to be twice as accurate. The technique is illustrated with a tumor and cyst lesions. The technique will be valuable in clinical studies whose purpose is to follow tumor response to therapy.